19/11/2017
آمار بازدید
 total : 76674
 online : 2
Dr. Maryam Neishabury
 

Maryam Neishabury

PhD: University of Wales (UK)

Associate Professor

e-mail: nneisha@gmail.com

           ma.neishabury@uswr.ac.ir

Tel. No.: 0098-21-22180138

Address: Genetics Research Center- University of Social Welfare and Rehabilitation- Kudakyar Alley- Daneshju Blvd.- Evin- Tehran- Iran

Link in scopus: http://www.scopus.com/authid/detail.url?origin=AuthorProfile&authorId=6506455707&zone=

Link in google scholar: https://scholar.google.com/citations?hl=en&user=h-7qYFgAAAAJ&view_op=list_works


Research Interest

Our research interest includes mechanism of hemoglobin switching, with a special focus on phenotype modifying factors in thalassemia.  We are currently working on protein- DNA interactions between beta globin locus control region and transcription factors involved in regulation of beta globin gene cluster.

 

Current Research Project:

Comparing the binding affinity of RUNX1 transcription factor for two oligonucleotides, representing  the single nucleotide polymorphism at the palindromic sequence of 5'HS4- Beta globin Locus Control Region

 

Selected Publications/commentaries

Neishabury, M., S. Zamani, A. Azarkeivan, S. S. Abedini, H. Darvish, F. Zamani & H. Najmabadi (2012) The modifying effect of Xmn1-HBG2 on thalassemic phenotype is associated with its linked elements in the beta globin locus control region, including the palindromic site at 5'HS4. Blood Cells Mol Dis, 48, 1-5.

Weatherall, D. J. (2012) Commentary on "The modifying effect of Xmn1-HBG2 on thalassemic phenotype is associated with its linked elements in the beta globin locus control region, including the palindromic site at 5' HS4" by M. Neishabury et al. Blood Cells Mol Dis, 48, 6.

Neishabury, M., F. Zamani, E. Keyhani, A. Azarkeivan, S. S. Abedini, M. S. Eslami, S. T. Kakroodi, M. J. Vesiehsari & H. Najmabadi (2013) The influence of the BCL11A polymorphism on the phenotype of patients with beta thalassemia could be affected by the beta globin locus control region and/or the Xmn1-HBG2 genotypic background. Blood Cells Mol Dis, 51, 80-4.

Talebi Kakroodi, S., Jafari Vesiehsari, M., Abedini, S.,  Ghobakhloo, S.,  Dehghani,  H., Keyhani,  e., Azarkeivan, A.,  Zamani, F.,  Najmabadi, H., Neishabury,M (2015) The role of BCL11A and HBS1L-MYB polymorphisms in predicting blood transfusion requirements of thalassemia patients with homozygous 5’HS4-LCR/Xmn1-HBG2 background. Genetis in the third millenium, 13, 3990-3993.

more

 

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